The diversity of experimental systems used to study the effects of Notch signaling, pleiotropy of Notch signals, and increased appreciation of Notch involvement in disease has made the Notch field explode in the past decade.

In 2007 we launched a biennial general Notch research meeting that aims to reflect the diversity of Notch research and bring together researchers from different fields and different experimental systems interested in Notch signaling. This second meeting was held in Athens in 2009. These meetings allow each of us to become better informed about what is happening in spheres of interest not immediately connected with our own, get a feeling about the trends and most exciting developments in the field, explore medical Notch applications, and hear and meet old and new players.

Interspersed with these general meetings, in alternating years, more focused smaller workshops help to explore specific thematic in more depth. The first such workshop with the title Notch and Cancer was held in 2008. The second such meeting with the title Notch and Stem Cells will be held in Athens in October 2010.

These meetings are sponsored by the not for profit foundation Fondation Santé (www.FondationSante.org) and benefit from the generosity of additional sponsors. The provisional program includes sessions and confirmed speakers. There will also be a poster session. The program will not be firmly set before early summer.